The nicest guy in the Midwest moves his family into a tough neighborhood in Los Angeles where not everyone appreciates his extreme neighborliness. That includes their new next-door neighbor Calvin.

Just because they're quadruplets, that doesn't mean these 10-year-olds always get along. But for all the bickering, they're loyal to the last.

The Russo family and friends are headed to Tuscany, Italy, to meet their long lost relatives... but when Alex tries to prove she's more than a seemingly carefree young Wizard, she inadvertently conjures a spell that creates a Good Alex and an Evil Alex. When Evil Alex gets roped into a charming young wizard's foreboding plan to take over the world, Good Alex must find a way to save her family and humankind, which leads to a monumental battle between the two versions of herself - all atop the Tower of Pisa.